Polyclonal Antibody to BCL-2(Phospho-Ser70), Rabbit
Biozol Catalog Number:
ABI-35-1063-50
Supplier Catalog Number:
35-1063-50
Alternative Catalog Number:
ABI-35-1063-50-50UL
Manufacturer:
Abeomics
Host:
Rabbit
Category:
Antikörper
Application:
IHC
Species Reactivity:
Human
Immunogen:
Peptide sequence around phosphorylation site of serine 70(R-T-S(p)-P-L) derived from Human BCL-2.
Alternative Names:
Bcl-2|| PPP1R50
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
