Polyclonal Antibody to ICAM-1 (Phospho-Tyr512), Rabbit
Biozol Catalog Number:
ABI-35-1081-50
Supplier Catalog Number:
35-1081-50
Alternative Catalog Number:
ABI-35-1081-50-50UL
Manufacturer:
Abeomics
Host:
Rabbit
Category:
Antikörper
Application:
WB
Species Reactivity:
Human
Immunogen:
Peptide sequence around phosphorylation site of tyrosine 512 (K-K-Y(p)-R-L) derived from Human ICAM-1.
Alternative Names:
ICA1|| ICAM1
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin a-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus. Greenwood J, et al. (2003) J Immunol, 171(4):2099-2108. Zhou Z, et al. (2005) Eur J Pharmacol, 513(1-2):1-8. Chen YH, et al. (2001) J Cell Biochem, 82(3):512-521
