Polyclonal Antibody to HDAC8 (Phospho-Ser39), Rabbit
Biozol Catalog Number:
ABI-35-1124-50
Supplier Catalog Number:
35-1124-50
Alternative Catalog Number:
ABI-35-1124-50-50UL
Manufacturer:
Abeomics
Host:
Rabbit
Category:
Antikörper
Application:
IF, IHC
Species Reactivity:
Human
Immunogen:
Peptide sequence around phosphorylation site of serine 39 (R-A-S(p)-M-V) derived from Human HDAC8.
Alternative Names:
HD8|| HDA8|| HDACL1
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by HDAC8 gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.
