Polyclonal Antibody to AFX (Phospho-Ser197), Rabbit
Biozol Catalog Number:
ABI-35-1132
Supplier Catalog Number:
35-1132
Alternative Catalog Number:
ABI-35-1132-100UL
Manufacturer:
Abeomics
Host:
Rabbit
Category:
Antikörper
Application:
IF, IHC, WB
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Peptide sequence around phosphorylation site of serine 197 (A-A-S(p)-M-D) derived from Human AFX.
Alternative Names:
AFX|| FOXO4|| AFX1|| Afxh
Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle.