Polyclonal Antibody to Alpha-Synuclein (Phospho-Ser129), Rabbit
Biozol Catalog Number:
ABI-35-1162-50
Supplier Catalog Number:
35-1162-50
Alternative Catalog Number:
ABI-35-1162-50-50UL
Manufacturer:
Abeomics
Host:
Rabbit
Category:
Antikörper
Application:
WB
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Peptide sequence around phosphorylation site of serine 129 (M-P-S(p)-E-E) derived from Human a-Synuclein.
Alternative Names:
NACP|| SYN|| SYUA
May be involved in the regulation of dopamine release and transport. Soluble protein, normally localized primarily at the presynaptic region of axons, which can form filamentous aggregates that are the major non amyloid component of intracellular inclusions in several neurodegenerative diseases (synucleinopathies). Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.
