Polyclonal Antibody to PKC Theta (Phospho-Ser695), Rabbit
Biozol Catalog Number:
ABI-35-1164
Supplier Catalog Number:
35-1164
Alternative Catalog Number:
ABI-35-1164-100UL
Manufacturer:
Abeomics
Host:
Rabbit
Category:
Antikörper
Application:
IHC, WB
Species Reactivity:
Human
Immunogen:
Peptide sequence around phosphorylation site of serine 695 (N-F-S(p)-F-M) derived from Human PKCth.
Alternative Names:
KPCT|| PKC-theta|| PKCQ|| PRKCQ|| PRKCT
This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Essential for T-cell receptor (TCR)-mediated T-cell activation, but is dispensable during TCR-dependent thymocyte development. Links the TCR signaling complex to the activation of NF-kappa-B in mature T lymphocytes. Required for interleukin-2 (IL2) production. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.
