Polyclonal Antibody to ASK1 (Phospho-Ser966), Rabbit

Product Overview

• Article Name: Polyclonal Antibody to ASK1 (Phospho-Ser966), Rabbit
• Biozol Catalog Number: ABI-35-1170
• Supplier Catalog Number: 35-1170
• Alternative Catalog Number: ABI-35-1170-100UL
• Manufacturer: Abeomics
• Host: Rabbit
• Category: Antikörper
• Application: IHC, WB
• Species Reactivity: Human, Mouse, Primate
• Immunogen: Peptide sequence around phosphorylation site of serine 966 (S-I-S(p)-L-P) derived from Human ASK1.
• Alternative Names: ASK-1|| M3K5|| MAP3K5|| MAPK/ERK kinase kinase 5|| MAPKKK5

Product Description

Component of a protein kinase signal transduction cascade. Phosphorylates and activates MAP2K4 and MAP2K6, which in turn activate the JNK and p38 MAP kinases, respectively. Overexpression induces apoptotic cell death. Zhang W, et al. (2005) J Biol Chem. 280(19): 19036-19044. Fujii K, et al. (2004) Oncogene. 23(29):5099-5104. Goldman EH, et al. (2004) J Biol Chem 2004 Mar 12, 279(11): 10442-10449. Zhang L, et al. (1999) Proc Natl Acad Sci U S A. 96(15): 8511-8515.

Product Properties

• Clonality: Polyclonal
• NCBI: 4217
• UniProt: Q99683
• Form: Purified
• Target: ASK1 (Phospho-Ser966)

Application Notes

• Application Dilute: Predicted MW: 155kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100