Polyclonal Antibody to p21Cip1 (Phospho-Thr145), Rabbit
Biozol Catalog Number:
ABI-35-1193
Supplier Catalog Number:
35-1193
Alternative Catalog Number:
ABI-35-1193-100UL
Manufacturer:
Abeomics
Host:
Rabbit
Category:
Antikörper
Application:
IHC
Species Reactivity:
Human
Immunogen:
Peptide sequence around phosphorylation site of threonine 145 (R-Q-T(p)-S-M) derived from Human p21Cip1.
Alternative Names:
CAP20|| CDK-interacting protein 1|| CDKN1|| CDKN1A|| CDN1A
May be the important intermediate by which p53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression.
