Anti-GRP94 / HSP90B1 (Endoplasmic Reticulum Marker) Monoclonal Antibody(Clone: HSP90B1/3168R), Clone: [HSP90B1/3168R], Rabbit

Product Overview

• Article Name: Anti-GRP94 / HSP90B1 (Endoplasmic Reticulum Marker) Monoclonal Antibody(Clone: HSP90B1/3168R), Clone: [HSP90B1/3168R], Rabbit
• Biozol Catalog Number: ABI-36-3311-20
• Supplier Catalog Number: 36-3311-20
• Alternative Catalog Number: ABI-36-3311-20-20UG
• Manufacturer: Abeomics
• Host: Rabbit
• Category: Antikörper
• Application: FACS, IHC
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Recombinant full-length human HSP90B1 protein
• Alternative Names: Glucose Regulated Protein 94, 94kDa glucose-regulated protein, Endoplasmin, Endothelial cell (HBMEC) glycoprotein (ECGP), Heat shock protein 90kDa beta member 1 (HSP90B1), Stress inducible tumor rejection antigen GP96, TRA1, Tumor rejection antigen-1 (gp96)

Product Description

Recognizes a protein of 94kDa, which is identified as the glucose-regulated protein 94 (grp94) and also tumor rejection antigen (gp96). Grp94 shows a high degree of sequence homology with the heat shock protein 90 (hsp90). This MAb is highly specific to grp94 and shows minimal cross-reaction with other members of the HSP90 family. Grps are a class of proteins unresponsive to heat shock and are induced by glucose deprivation. Grp94 has been briefly studied as a prognostic factor in breast cancer.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [HSP90B1/3168R]
• NCBI: 7184
• UniProt: P14625

Application Notes

• Application Dilute: Flow Cytometry (1-2ug/million cells),Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95&degC followed by coolin