Recognizes a 67kDa transmembrane protein, which is identified as CD5 (HLDA I, WS Code T 29HLDA III, WS Code T 530). The CD5 antigen is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms.
Flow Cytometry (1-2ug/million cells), Immunofluorescence (1-2ug/ml), Functional Studies (Order Ab without BSA & Azide), Immunoprecipitation (0.5-1ug/500ug protein lysate),
* VAT and and shipping costs not included. Errors and price changes excepted
