Anti-Cytokeratin, pan (Epithelial Marker) Monoclonal Antibody(Clone: AE-1/AE-3)-FITC, Clone: [AE-1/AE-3], Mouse
Biozol Catalog Number:
ABI-36-3749
Supplier Catalog Number:
36-3749
Alternative Catalog Number:
ABI-36-3749-0.5AT100MLATUG/ML
Manufacturer:
Abeomics
Host:
Mouse
Category:
Antikörper
Application:
FACS, IF
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Human epidermal keratin
Conjugation:
FITC
Alternative Names:
K1B, KRT1B, Keratin, type II cytoskeletal 1b, K77, CK-1B, Keratin 1B, Keratin-77, Cytokeratin-1B, Type-II Keratin Kb39
Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 40kDa (CK19). Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. AE-1/AE-3 is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It has been used to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and has shown high sensitivity in the recognition of epithelial cells and carcinomas.
