Recombinant hMART-1 protein (DT101 & BC199), Extract of pigmented melanoma metastases from lymph nodes (HMB45)
Alternative Names:
Melanoma antigen recognized by T-cells 1 (MART-1), MLAN-A, PMEL17
This antibody cocktail recognizes two melanoma-specific proteins, which include MART-1 and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. A cocktail of these two markers is sensitive for labeling formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95&degC followed by cooling at RT for 20 minutes),
Fig. 1: Formalin-fixed, paraffin-embedded human Melanoma stained with Melanoma Marker Mouse Monoclonal Antibody (DT101+ BC199 + HMB45).
Fig. 2: Formalin-fixed, paraffin-embedded human Melanoma stained with Melanoma Marker Mouse Monoclonal Antibody (DT101+ BC199 + HMB45).
* VAT and and shipping costs not included. Errors and price changes excepted
