Anti-Cathepsin L Monoclonal Antibody (Clone: 33/2), Clone: [33/2], Mouse
Biozol Catalog Number:
ABI-39-1013
Supplier Catalog Number:
39-1013
Alternative Catalog Number:
ABI-39-1013-100UG/VIAL
Manufacturer:
Abeomics
Host:
Mouse
Category:
Antikörper
Application:
IHC-Fr, WB
Species Reactivity:
Human
Immunogen:
Procathepsin L isolated from the human lung cancer cell line EPLC 32M1.
Alternative Names:
Cathepsin L, Major excreted protein, CTSL1
Cathepsin L is a lysosomal cysteine proteinase with a major role in intracellular protein catabolism. It also shows the most potent collagenolytic and elastinolytic activity in vitro of any of the cathepsins. Cathepsin L has been implicated in pathologic processes including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. Human liver cathepsin L consists of a heavy chain of about 25 kD and a light chain of about 5 kD. The gene is mapped to 9q21-q22. Cathepsin L is required for endothelial progenitor cell-induced neovascularization.
