Anti-Desmin Monoclonal Antibody (Clone: DE-U-10), Clone: [DE-U-10], Mouse

Product Overview

• Article Name: Anti-Desmin Monoclonal Antibody (Clone: DE-U-10), Clone: [DE-U-10], Mouse
• Biozol Catalog Number: ABI-39-1031
• Supplier Catalog Number: 39-1031
• Alternative Catalog Number: ABI-39-1031-100UG/VIAL
• Manufacturer: Abeomics
• Host: Mouse
• Category: Antikörper
• Application: WB
• Species Reactivity: Human
• Immunogen: Desmin from pig stomach.
• Alternative Names: Desmin, Des

Product Description

Desmin belongs to the type III family of intermediate filaments, a class of cytoskeletal elements. DES gene encodes desmin, a muscle-specific cytoskeletal protein found in smooth, cardiac, and heart muscles. Tidball(1992) found that desmin was codistributed with actin thin filaments within the cellular processes of myotendinous junctions in frog skeletal muscle. DES gene contains 9 exons and spans about 8.4 kb. By in situ hybridization, Viegas-Pequignot et al.(1989) localized the gene to 2q35. Desmin mutation responsible for idiopathic dilated cardiomyopathy.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [DE-U-10]
• NCBI: 64362
• UniProt: P48675
• Purity: Ascites
• Target: Desmin
• Antibody Type: Monoclonal Antibody

Application Notes

• Application Dilute: Western blot : 2µg/ml, Immunohistochemistry(Paraffin-embedded Section) : 2-4µg/ml

Images

Figure 1: Anti-Desmin monoclonal antibody(39-1031). IHC(P): Rat Cardiac Muscle Tissue.

Figure 2: Anti-Desmin monoclonal antibody(39-1031). Western blotting: Lanes: Anti Desmin(39-1031) at 0.5 ug/ml.Lane 1: Rat Skeletal Muscle Tissue Lysate at 50ug, Lane 2: Rat Cardiac Muscle Tissue Lysate at 50ug, Lane 3: Mouse Skeletal Muscle Tissue Lysate at 50ug, Lane 4: Mouse Cardiac Muscle Tissue Lysate at 50ug. Predicted band size: 53 kDa: Observed band size: 53 kDa.