Biotinylated Human ACE2 / ACEH Protein, His,Avitag(TM) (MALS verified)
Biozol Catalog Number:
ABS-AC2-H82E6-25UG
Supplier Catalog Number:
AC2-H82E6-25ug
Alternative Catalog Number:
ABS-AC2-H82E6-25UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Biotin
Angiotensinconverting enzyme 2 (ACE2) is also known as ACEH (ACE homolog), is an integral membrane protein with considerable homologous to ACE, which belongs to the peptidase M2 family. ACE2 is an exopeptidase that catalyses the conversion of angiotensin I to the nonapeptide angiotensin, or the conversion of angiotensin II to angiotensin 17. ACE2 may be an important regulator of heart function. In case of human coronaviruses SARS and HCoVNL63 infections, ACE2 serve as functional receptor for the spike glycoprotein of both coronaviruses. ACE2 is activated by chloride and fluoride, but not bromide and Inhibited by MLN4760, cFP_Leu, and EDTA, but not by the ACE inhibitors linosipril, captopril and enalaprilat. ACE2 is active from pH 6 to 9, and the optimum pH is 6.5 in the presence of 1 M NaCl. - Proteine/Peptide
