Human / Cynomolgus Activin RIIA / ACVR2A Protein, His Tag (MALS & SPR verified), Unconjugated

Product Overview

• Article Name: Human / Cynomolgus Activin RIIA / ACVR2A Protein, His Tag (MALS & SPR verified), Unconjugated
• Biozol Catalog Number: ABS-ACA-H5243-200UG
• Supplier Catalog Number: ACA-H5243-200ug
• Alternative Catalog Number: ABS-ACA-H5243-200UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human, Monkey
• Conjugation: Unconjugated

Product Description

Activin receptor type2A (ACVR2A) is also known as Activin receptor type IIA, ACTRIIA, ACTRIIA and ACVR2,which is singlepass type I membrane protein. ACVR2A belongs to the protein kinase superfamily,TKL Ser/Thr protein kinase family and TGFB receptor subfamily.On ligand binding,ACVR2A can forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators.ACVR2A is Receptor for activin A, activin B and inhibin A as well. Several type I I activin receptors have been identified and bind to different activins with different affinities. - Proteine/Peptide

Product Properties

• Molecular Weight: 15.4 kDa
• Tag: N-10*His
• NCBI: 27037
• Buffer: PBS, pH7.4
• Purity: 90%
• Form: Powder
• Target: Activin RIIA

Images

Immobilized Human / Cynomolgus Activin RIIA Protein, His Tag (Cat. No. ACA-H5243) at 1 µg/mL (100 µL/well) can bind Bimagrumab with a linear range of 0.05-1 ng/mL (Routinely tested).

Human / Cynomolgus Activin RIIA Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

ACA-H5243-200ug