Human Activin RIB & Activin RIIB Protein, Fc Tag&Fc Tag, Unconjugated

Product Overview

• Article Name: Human Activin RIB & Activin RIIB Protein, Fc Tag&Fc Tag, Unconjugated
• Biozol Catalog Number: ABS-ACB-H5253-100UG
• Supplier Catalog Number: ACB-H5253-100ug
• Alternative Catalog Number: ABS-ACB-H5253-100UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Activins are dimeric growth and differentiation factors which belong to the transforming growth factorbeta (TGFbeta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligandbinding extracellular domain with cysteinerich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This gene encodes activin A type IIB receptor, which displays a 3 to 4fold higher affinity for the ligand than activin A type II receptor. - Proteine/Peptide

Product Properties

• Molecular Weight: 37 kDa & 39.1 kDa
• Tag: C-Fc | C-Fc
• NCBI: 36896
• Buffer: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
• Purity: 90%
• Form: Powder
• Target: Activin RIB & Activin RIIB

Images

Immobilized Human Activin A Protein, Tag Free (Cat. No. ACA-H421b) at 5 µg/mL (100 µL/well) can bind Human Activin RIB & Activin RIIB Protein, Fc Tag&Fc Tag (Cat. No. ACB-H5253) with a linear range of 0.3-10 ng/mL (QC tested).

Immobilized Human latent GDF-8, His Tag (Cat. No. GD8-H5243) at 5 µg/mL (100 µL/well) can bind Human Activin RIB & Activin RIIB Protein, Fc Tag&Fc Tag (Cat. No. ACB-H5253) with a linear range of 0.005-0.156 µg/mL (Routinely tested).

Human Activin RIB & Activin RIIB Protein, Fc Tag&Fc Tag on SDS-PAGE under non-reducing (NR) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.