Human Activin RIB / ACVR1B Protein, His Tag, Unconjugated
Biozol Catalog Number:
ABS-ACB-H52H4-100UG
Supplier Catalog Number:
ACB-H52H4-100ug
Alternative Catalog Number:
ABS-ACB-H52H4-100UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Unconjugated
Activin receptor type1B (ACVR1B) is also known as Activin receptorlike kinase 4 (ALK4), Serine/threonineprotein kinase receptor R2 (SKR2), which belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family and TGFB receptor subfamily. ACVR1B contains one GS domain and one protein kinase domain. The catalytic activity of ACVR1B is ''ATP + [receptorprotein] = ADP + [receptorprotein] phosphate. ACVR1B acts as a transducer of activin or activin like ligands (e.g., inhibin) signals. Activin binds to either ACVR2A or ACVR2B and then forms a complex with ACVR1B. These go on to recruit the RSMADs SMAD2 or SMAD3. ACVR1B also transduces signals of nodal, GDF1, and Vg1. - Proteine/Peptide
