Human ADIPOR1 Protein, Flag,His Tag (Detergent), Unconjugated, Insect 20 ug
Biozol Catalog Number:
ABS-AD1-H55D3-20UG
Supplier Catalog Number:
AD1-H55D3-20ug
Alternative Catalog Number:
ABS-AD1-H55D3-20UG
Manufacturer:
AcroBiosystems
Host:
Insect
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Unconjugated
Adiponectin Receptor 1 (AdipoR1) is a pivotal receptor mediating the metabolic effects of the adipokine adiponectin. AdipoR1 features seven transmembrane domains with an intracellular Nterminus and an extracellular Cterminus responsible for adiponectin binding. AdipoR1 is predominantly expressed in skeletal muscle and can activate adenosine monophosphateactivated protein kinase (AMPK). This activation leads to the phosphorylation of ACC and the subsequent upregulation of CPT1A, which together critically enhance mitochondrial fatty acid betaoxidation. Dysfunction in this AdipoR1driven pathway is closely associated with impaired fatty acid oxidation and dyslipidemia. AdipoR1 represents a significant therapeutic target for metabolic disorders involving lipid dysregulation. - Proteine/Peptide
Immobilized Human ADIPOR1 Protein, Flag,His Tag (Cat. No. AD1-H55D3) at 1 µg/mL (100 µL/well) can bind Anti-ADIPOR1 Antibody, Rabbit IgG1 with a linear range of 0.2-5 ng/mL (QC tested).
AD1-H55D3-20ug
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