Human ACHE / Acetylcholinesterase Protein, His Tag (active enzyme), Unconjugated

Product Overview

• Article Name: Human ACHE / Acetylcholinesterase Protein, His Tag (active enzyme), Unconjugated
• Biozol Catalog Number: ABS-AHE-H52H3-20UG
• Supplier Catalog Number: AHE-H52H3-20ug
• Alternative Catalog Number: ABS-AHE-H52H3-20UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

The enzyme acetylcholinesterase, also known as AChE or acetylhydrolase, is the primary cholinesterase in the body. It is a serine hydrolase whose primary function is to catalyzes the breakdown of acetylcholine(ACh) and of some other choline esters that function as neurotransmitters. AChE is found at mainly neuromuscular junctions and in chemical synapses of the cholinergic type, where its activity serves to terminate synaptic transmission. Acetylcholine deficit has been found in Alzheimers disease (AD) ans is associated with cognetive decline. Therefore, AChE has been reported to be a viable therapeutic target for the treatment of AD and other dementias. To this end, acetylcholinesterase inhibitors (AChEIs) are commonly used. - Proteine/Peptide

Product Properties

• Molecular Weight: 66.5 kDa
• Tag: C-10*His
• NCBI: 22303
• Buffer: PBS, pH7.4
• Purity: 95%
• Form: Powder
• Target: ACHE

Images

Human ACHE, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.