Human Angiogenin / RNASE5 Protein, His Tag (SPR verified), Unconjugated, E. coli
Biozol Catalog Number:
ABS-ANN-H5149-100UG
Supplier Catalog Number:
ANN-H5149-100ug
Alternative Catalog Number:
ABS-ANN-H5149-100UG
Manufacturer:
AcroBiosystems
Host:
E. coli
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Unconjugated
Binds to actin on the surface of endothelial cells, once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA. Cleaves tRNA within anticodon loops to produce tRNAderived stressinduced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs). Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo - Proteine/Peptide
