Human Apolipoprotein E / APOE4 Protein, Tag Free (MALS verified), Unconjugated
Biozol Catalog Number:
ABS-APE-H5215-1MG
Supplier Catalog Number:
APE-H5215-1mg
Alternative Catalog Number:
ABS-APE-H5215-1MG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Unconjugated
APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoproteinmediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to highdensity lipoproteins (HDL). It also binds a wide range of cellular receptors including the LDL receptor/LDLR, the LDL receptorrelated proteins LRP1, LRP2 and LRP8 and the very lowdensity lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOEcontaining lipoprotein particles. - Proteine/Peptide
