Human B7-H4 Protein, Fc Tag, low endotoxin, Unconjugated

Product Overview

• Article Name: Human B7-H4 Protein, Fc Tag, low endotoxin, Unconjugated
• Biozol Catalog Number: ABS-B74-H5256-1MG
• Supplier Catalog Number: B74-H5256-1mg
• Alternative Catalog Number: ABS-B74-H5256-1MG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Vset domaincontaining Tcell activation inhibitor 1 (VTCN1) is also known as Immune costimulatory protein B7H4, Protein B7S1, Tcell costimulatory molecule B7x, B7H4, which belongs to the immunoglobulin superfamily and BTN/MOG family. VTCN1 contains two Iglike Vtype (immunoglobulinlike) domains. The expression of VTCN1 is upregulated by IL6 and IL10 and is inhibited by GMCSF and IL4 on antigenpresenting cells (APCs). VTCN1 / B7H4 negatively regulates Tcellmediated immune response by inhibiting Tcell activation, proliferation, cytokine production and development of cytotoxicity. VTCN1 involved in promoting epithelial cell transformation. - Proteine/Peptide

Product Properties

• Molecular Weight: 51.8 kDa
• Tag: C-Fc
• NCBI: 7
• Buffer: PBS, pH7.4
• Expression System: Phe 29 - Ala 258
• Purity: 95%
• Form: Powder
• Target: B7-H4

Images

B74-H5256-1mg