Cynomolgus B7-H7 / HHLA2 Protein, His Tag (MALS verified), Unconjugated, Human
Biozol Catalog Number:
ABS-B77-C52H3-1MG
Supplier Catalog Number:
B77-C52H3-1mg
Alternative Catalog Number:
ABS-B77-C52H3-1MG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Monkey
Conjugation:
Unconjugated
B7H7 (HHLA2) is a newly identified B7 family member that regulates human Tcell functions. B7H7 was previously known as human endogenous retrovirusH long terminal repeat associating 2 (HHLA2) with unidentified function. Recently, B7H7 has been identified as a specific ligand for human CD28H. The B7H7CD28H pathway strongly promoted CD4+ Tcell proliferation and cytokine production via an AKTdependent signaling cascade in the presence of TCR signaling, suggesting B7H7 comprises a new costimulatory pathway. The first IgV domain of B7H7, which presumably binds to a putative receptor, shows the highest homology to other B7 family members. - Proteine/Peptide
