Cynomolgus BAFFR / TNFRSF13C Protein, His Tag (MALS verified), Unconjugated, Human
Biozol Catalog Number:
ABS-BAR-C52H4-100UG
Supplier Catalog Number:
BAR-C52H4-100ug
Alternative Catalog Number:
ABS-BAR-C52H4-100UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Monkey
Conjugation:
Unconjugated
BAFF receptor (Bcell activating factor receptor, BAFFR), also known as tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), is a membrane protein of the TNF receptor superfamily which recognizes BAFF. Bcell activating factor (BAFF) enhances Bcell survival in vitro and is a regulator of the peripheral Bcell population. Overexpression of BAFF in mice results in mature Bcell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. - Proteine/Peptide
Immobilized Human BAFF, Fc Tag, active trimer (Cat. No. BAF-H5261) at 1 µg/mL (100 µL/well) can bind Cynomolgus BAFFR, His Tag (Cat. No. BAR-C52H4) with a linear range of 0.4-3 ng/mL (QC tested).
Immobilized Cynomolgus BAFFR, His Tag (Cat. No. BAR-C52H4) at 1 µg/mL (100 µL/well) can bind Anti-BAFFR Antibody, Human IgG1 with a linear range of 0.1-0.8 ng/mL (Routinely tested).
Cynomolgus BAFFR, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
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