Human BAFFR / TNFRSF13C Protein, His Tag (MALS verified), Unconjugated
Biozol Catalog Number:
ABS-BAR-H52H3-1MG
Supplier Catalog Number:
BAR-H52H3-1mg
Alternative Catalog Number:
ABS-BAR-H52H3-1MG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Unconjugated
BAFF receptor (Bcell activating factor receptor, BAFFR), also known as tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), is a membrane protein of the TNF receptor superfamily which recognizes BAFF. Bcell activating factor (BAFF) enhances Bcell survival in vitro and is a regulator of the peripheral Bcell population. Overexpression of BAFF in mice results in mature Bcell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. - Proteine/Peptide
