Anti-Bevacizumab Antibody (AY12) (recommended for neutralizing assay), Unconjugated, Multiple

Product Overview

• Article Name: Anti-Bevacizumab Antibody (AY12) (recommended for neutralizing assay), Unconjugated, Multiple
• Biozol Catalog Number: ABS-BEB-Y12-1MG
• Supplier Catalog Number: BEB-Y12-1mg
• Alternative Catalog Number: ABS-BEB-Y12-1MG
• Manufacturer: AcroBiosystems
• Host: Multiple
• Category: Antikörper
• Species Reactivity: Mouse
• Conjugation: Unconjugated

Product Description

A recombinant humanized monoclonal IgG1 antibody that binds to and inhibits the biologic activity of human vascular endothelial growth factor (VEGF). Bevacizumab contains human framework regions and the complementaritydetermining regions of a murine antibody that binds to VEGF. Bevacizumab is produced in a Chinese Hamster Ovary mammalian cell expression system in a nutrient medium containing the antibiotic gentamicin and has a molecular weight of approximately 149 kilodaltons. - Antikörper

Product Properties

• Buffer: Tris with Glycine, Arginine and NaCl, pH7.5
• Purity: 0.95
• Form: Powder
• Target: Bevacizumab

Images

Anti-Bevacizumab Antibodies bridging ELISA for Anti-Drug Antibody (ADA) assay development. Immobilized bevacizumab at 5 µg/mL, add increasing concentrations of Anti-Bevacizumab Antibody (AY12) (Cat. No. BEB-Y12, 10% human serum) and then add biotinylated bevacizumab at 5 µg/mL. Detection was performed using HRP-conjugated streptavidin with a sensitivity of 62 ng/mL (QC tested).

Demonstration of the specificity of Anti-Bevacizumab Antibody (AY12) (Cat. No. BEB-Y12) to the bevacizumab.

Anti-Bevacizumab Antibody (AY12) on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 0.95.

BEB-Y12-1mg