Human Caspase-1 Protein, His Tag&Tag Free, Unconjugated, E. coli 200 ug

Product Overview

• Article Name: Human Caspase-1 Protein, His Tag&Tag Free, Unconjugated, E. coli 200 ug
• Biozol Catalog Number: ABS-CA1-H51W3-200UG
• Supplier Catalog Number: CA1-H51W3-200ug
• Alternative Catalog Number: ABS-CA1-H51W3-200UG
• Manufacturer: AcroBiosystems
• Host: E. coli
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Caspases are an evolutionary conserved family of cysteinedependent proteases that are involved in many vital cellular processes including apoptosis, proliferation, differentiation and inflammatory response. Dysregulation of caspasemediated apoptosis and inflammation has been linked to the pathogenesis of various diseases such as inflammatory diseases, neurological disorders, metabolic diseases, and cancer.The members of the caspase family are grouped based on their functional contribution in inflammation (caspases1, 4, 5, and 11) and involvement in cell death (initiation: caspases2, 8, 9, and 10, execution: caspases3, 6, and 7) or by their consensus recognition sequences. Inflammatory caspases recognize the sequence TrpGluHisAsp and are classified as group I. Whilst group II and group III recognize AspGluXAsp and (Leu/Val)GluXAsp, respectively. - Proteine/Peptide

Product Properties

• Molecular Weight: 21.9 kDa & 10.4 kDa
• Tag: N-10*His | Native
• NCBI: 29466
• Buffer: 20 mM Tris, 300 mM NaCl, 0.5 M Arginine, pH8.0
• Purity: 90%
• Form: Liquid
• Target: Caspase-1

Images

Human Caspase-1 Protein, His Tag&Tag Free on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.