Human Caspase-1 Protein, His Tag&Tag Free, Unconjugated, E. coli
Biozol Catalog Number:
ABS-CA1-H51W3-25UG
Supplier Catalog Number:
CA1-H51W3-25ug
Alternative Catalog Number:
ABS-CA1-H51W3-25UG
Manufacturer:
AcroBiosystems
Host:
E. coli
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Unconjugated
Caspases are an evolutionary conserved family of cysteinedependent proteases that are involved in many vital cellular processes including apoptosis, proliferation, differentiation and inflammatory response. Dysregulation of caspasemediated apoptosis and inflammation has been linked to the pathogenesis of various diseases such as inflammatory diseases, neurological disorders, metabolic diseases, and cancer.The members of the caspase family are grouped based on their functional contribution in inflammation (caspases1, 4, 5, and 11) and involvement in cell death (initiation: caspases2, 8, 9, and 10, execution: caspases3, 6, and 7) or by their consensus recognition sequences. Inflammatory caspases recognize the sequence TrpGluHisAsp and are classified as group I. Whilst group II and group III recognize AspGluXAsp and (Leu/Val)GluXAsp, respectively. - Proteine/Peptide
