Human Cadherin-11 Protein, His Tag (MALS verified), Unconjugated

Catalog Number: ABS-CA1-H52H3-100UG
Article Name: Human Cadherin-11 Protein, His Tag (MALS verified), Unconjugated
Biozol Catalog Number: ABS-CA1-H52H3-100UG
Supplier Catalog Number: CA1-H52H3-100ug
Alternative Catalog Number: ABS-CA1-H52H3-100UG
Manufacturer: AcroBiosystems
Host: Human
Category: Proteine/Peptide
Species Reactivity: Human
Conjugation: Unconjugated
Cadherin11 is a type II cadherin which mediates celltocell homophilic interactions. Cadherin11 is mainly expressed on mesenchymal cells and is essential for tissue migration and organization during embryogenesis, while its expression on epithelial cancer cells is implicated in tumor progression and metastasis suggesting a potential role in the epithelialtomesenchymal transition phenomenon. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. In addition, cadherin11 has been shown to increase the invasive capacity of Fibroblastlike Synoviocytes (FLS) and consequently be involved in the formation of the rheumatoid pannus. - Proteine/Peptide
Molecular Weight: 63.8 kDa
Tag: C-10*His
NCBI: 55287
Buffer: PBS, 0.5 M Arginine, pH7.4
Purity: 90%
Form: Powder
Target: Cadherin-11
Human Cadherin-11 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.