Human Carbonic Anhydrase IX / CA9 (138-414) Protein, His Tag (MALS verified), Unconjugated
Biozol Catalog Number:
ABS-CA9-H5220-1MG
Supplier Catalog Number:
CA9-H5220-1mg
Alternative Catalog Number:
ABS-CA9-H5220-1MG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Unconjugated
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes. CAs form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa), a reversible reaction that occurs rather slowly in the absence of a catalyst. One of the functions of the enzyme in animals is to interconvert carbon dioxide and bicarbonate to maintain acidbase balance in blood and other tissues, and to help transport carbon dioxide out of tissues. The active site of most carbonic anhydrases contains a zinc ion. There are at least five distinct CA families (alpha, beta, gamma, delta and epsilon). Carbonic anhydrase 9 (CA9 / CAIX) is also known as Membrane antigen MN (MN), Renal cell carcinomaassociated antigen G250, which belongs to the alphacarbonic anhydrase family. CA9 / CAIX with an optimal activity at pH 6.49. Reversible hydration of carbon dioxide. CA IX participates in pH regulation. CA9 may be involved in the control of cell proliferation and transformation. CAIX appears to be a novel specific biomarker for a cervical neoplasia. - Proteine/Peptide
