Human CBLB / RNF56 Protein, His Tag, Unconjugated, E. coli
Biozol Catalog Number:
ABS-CBB-H5148-1MG
Supplier Catalog Number:
CBB-H5148-1mg
Alternative Catalog Number:
ABS-CBB-H5148-1MG
Manufacturer:
AcroBiosystems
Host:
E. coli
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Unconjugated
Casitas Blineage lymphoma protooncogene b (CBLB) is also known as RNF56. E3 ubiquitinprotein ligase which accepts ubiquitin from specific E2 ubiquitinconjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome. Negatively regulates TCR (Tcell receptor), BCR (Bcell receptor) and FCER1 (high affinity immunoglobulin epsilon receptor) signal transduction pathways. Slightly promotes SRC ubiquitination. May be involved in EGFR ubiquitination and internalization. May be functionally coupled with the E2 ubiquitinprotein ligase UB2D3. Expressed in placenta, heart, lung, kidney, spleen, ovary and testis, as well as fetal brain and liver and hematopoietic cell lines, but not in adult brain, liver, pancreas, salivary gland, or skeletal muscle. - Proteine/Peptide
