Human CCL2 / MCP-1 Protein, Fc Tag (MALS verified), Unconjugated
Biozol Catalog Number:
ABS-CC2-H5255-50UG
Supplier Catalog Number:
CC2-H5255-50ug
Alternative Catalog Number:
ABS-CC2-H5255-50UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Unconjugated
Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of Nterminal cysteine residues of the mature peptide. CCL2, a member of the CC subfamily, is characterized by two adjacent cysteine residues. CCL2 displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. Elevated expression of the encoded protein is associated with severe acute respiratory syndrome coronavirus 2 (SARSCoV2) infection. - Proteine/Peptide
50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Purity:
90%
Form:
Powder
Target:
CCL2
Immobilized Human CCL2, Fc Tag (Cat. No. CC2-H5255) at 5 µg/mL (100 µL/well) can bind Human CCR2 Full Length Protein, Flag,His Tag (Cat. No. CC2-H52D4) with a linear range of 0.005-0.313 µg/mL (QC tested).
Immobilized Human CCL2, Fc Tag (Cat. No. CC2-H5255) at 5 µg/mL (100 µL/well) can bind Anti-MCP-1 / CCL2 Antibody, Mouse Fc (1B7) with a linear range of 0.2-5 ng/mL (Routinely tested).
Human CCL2, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
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