Human CCR4 Full Length Protein, Flag,His Tag (Detergent), Unconjugated
Biozol Catalog Number:
ABS-CC4-H52D3-20UG
Supplier Catalog Number:
CC4-H52D3-20ug
Alternative Catalog Number:
ABS-CC4-H52D3-20UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Unconjugated
CC chemokine receptor type 4 is a receptor for the following CC chemokines: CCL2, CCL4, CCL5, CCL17, CCL22, belongs to the G proteincoupled receptor family. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. CCR4 is often expressed on leukemic cells in cutaneous Tcell lymphoma (CTCL). Mogamulizumab is a humanized monoclonal antibody targeted at CCR4and is an investigational drug for CTCL. - Proteine/Peptide
