Human CCL24/Eotaxin-2 Protein, His Tag (HPLC verified), Unconjugated
Biozol Catalog Number:
ABS-CC4-H52H1-100UG
Supplier Catalog Number:
CC4-H52H1-100ug
Alternative Catalog Number:
ABS-CC4-H52H1-100UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Unconjugated
CC motif chemokine ligand 24 (CCL24), also known as eotaxin2, belongs to CC chemokines like MCP1, and it mainly chemoattracts eosinophils. CCL24 can promote the separation of eosinophils from endothelial cells and then combine with its sole ligand to promote eosinophils to enter the tissue. CCL24 was not originally found in eosinophils but was first isolated from monocytes. Latest, it was found that the expression of CCL24 in the bronchial epithelial cells of asthma patients increased. CCL24 promotes immune cell trafficking and activation as well as profibrotic activities through the CCR3 receptor (CC chemokine receptor type 3). Both CCL24 and CCR3 is involved in lung and skin inflammation and fibrosis. - Proteine/Peptide
