CCL7, also known as monocyte chemotactic protein3 (MCP3), is a CC (cysteine-cysteine) chemokine that is 11-18 kDa in size depending on the level of glycosylation. Its gene has been mapped to chromosome 17q11.2q12 and is expressed in response to endogenous cytokines or exogenous bacterial products. This protein shares 60-71% homology with MCP1 and MCP2 chemokines and consequently binds similar receptors. Receptors CCR1, CCR2, CCR3, and CCR5 have been identified to bind CCL7 in both progenitor and immune cells. - Proteine/Peptide
