Biotinylated Human CCR7 Full Length Protein, His,Flag Tag&Avitag(TM) (Detergent)
Biozol Catalog Number:
ABS-CC7-H82D4-100UG
Supplier Catalog Number:
CC7-H82D4-100ug
Alternative Catalog Number:
ABS-CC7-H82D4-100UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Biotin
The monoclonal antibody mAb729 reacts with the human CC chemokine receptor, CCR7. The protein encoded by this gene is a member of the G proteincoupled receptor family. This receptor was identified as a gene induced by the EpsteinBarr virus (EBV),and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (CC motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. - Proteine/Peptide
