Human CD30 / TNFRSF8 Protein, Fc Tag (MALS verified), Unconjugated

Product Overview

• Article Name: Human CD30 / TNFRSF8 Protein, Fc Tag (MALS verified), Unconjugated
• Biozol Catalog Number: ABS-CD0-H5250-100UG
• Supplier Catalog Number: CD0-H5250-100ug
• Alternative Catalog Number: ABS-CD0-H5250-100UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Human CD30 is also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. TNFRSF8 is expressed by activated, but not by resting, T and B cells. Also, CD30 is expressed on classical Hodgkin Lymphoma cells together with CD15. CD30 is the receptor for TNFSF8/CD30L. CD30 can interact with TRAF2 and TRAF5, and mediate the signal transduction that leads to the activation of NFkappaB. TNFRSF8 may play a role in the regulation of cellular growth and transformation of activated lymphoblasts. TNFRSF8 is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. - Proteine/Peptide

Product Properties

• Molecular Weight: 64.62 kDa
• Tag: C-Fc
• NCBI: 001234
• Buffer: 50 mM Tris, 100 mM Glycine, pH7.5
• Purity: 95%
• Form: Powder
• Target: CD30

Images

Immobilized Human CD30 Ligand, Mouse IgG2a Fc Tag, low endotoxin (Cat. No. CDL-H525b) at 2 µg/mL (100 µL/well) can bind Human CD30, Fc Tag (Cat. No. CD0-H5250) with a linear range of 0.2-4 ng/mL (QC tested).

Human CD30, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.