Human CD30 / TNFRSF8 Protein, His Tag, Unconjugated

Catalog Number: ABS-CD0-H52H5-1MG
Article Name: Human CD30 / TNFRSF8 Protein, His Tag, Unconjugated
Biozol Catalog Number: ABS-CD0-H52H5-1MG
Supplier Catalog Number: CD0-H52H5-1mg
Alternative Catalog Number: ABS-CD0-H52H5-1MG
Manufacturer: AcroBiosystems
Host: Human
Category: Proteine/Peptide
Species Reactivity: Human
Conjugation: Unconjugated
Human CD30 is also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. TNFRSF8 is expressed by activated, but not by resting, T and B cells. Also, CD30 is expressed on classical Hodgkin Lymphoma cells together with CD15. CD30 is the receptor for TNFSF8/CD30L. CD30 can interact with TRAF2 and TRAF5, and mediate the signal transduction that leads to the activation of NFkappaB. TNFRSF8 may play a role in the regulation of cellular growth and transformation of activated lymphoblasts. TNFRSF8 is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. - Proteine/Peptide
Molecular Weight: 40.4 kDa
Tag: C-10*His
NCBI: 001234
Buffer: PBS, pH7.4
Purity: 90%
Form: Powder
Target: CD30
Immobilized Human CD30, His Tag (Cat. No. CD0-H52H5) at 1 µg/mL (100 µL/well) can bind Monoclonal Anti-Human CD30 Human Antibody, Human IgG1 with a linear range of 0.2-2 ng/mL (QC tested).
Immobilized Monoclonal Anti-Human CD30 Human Antibody, Human IgG1 at 2 µg/mL (100 µL/well) can bind Human CD30, His Tag (Cat. No. CD0-H52H5) with a linear range of 0.6-5 ng/mL (Routinely tested).
Human CD30, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.