Biotinylated Human CD30 / TNFRSF8 Protein, Fc,Avitag(TM) (MALS verified)

Catalog Number: ABS-CD0-H82F4-25UG
Article Name: Biotinylated Human CD30 / TNFRSF8 Protein, Fc,Avitag(TM) (MALS verified)
Biozol Catalog Number: ABS-CD0-H82F4-25UG
Supplier Catalog Number: CD0-H82F4-25ug
Alternative Catalog Number: ABS-CD0-H82F4-25UG
Manufacturer: AcroBiosystems
Host: Human
Category: Proteine/Peptide
Species Reactivity: Human
Conjugation: Biotin
Human CD30 is also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. TNFRSF8 is expressed by activated, but not by resting, T and B cells. Also, CD30 is expressed on classical Hodgkin Lymphoma cells together with CD15. CD30 is the receptor for TNFSF8/CD30L. CD30 can interact with TRAF2 and TRAF5, and mediate the signal transduction that leads to the activation of NFkappaB. TNFRSF8 may play a role in the regulation of cellular growth and transformation of activated lymphoblasts. TNFRSF8 is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. - Proteine/Peptide
Molecular Weight: 66.6 kDa
Tag: C-Fc & C-Avi
NCBI: 001234
Buffer: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Purity: 90%
Form: Powder
Target: CD30
Immobilized Human CD30 Ligand, His Tag, low endotoxin (Cat. No. CDL-H524b) at 5 µg/mL (100 µL/well) can bind Biotinylated Human CD30, Fc,Avitag (Cat. No. CD0-H82F4) with a linear range of 0.6-20 ng/mL (QC tested).
Biotinylated Human CD30, Fc,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.