Human CD30 is also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. TNFRSF8 is expressed by activated, but not by resting, T and B cells. Also, CD30 is expressed on classical Hodgkin Lymphoma cells together with CD15. CD30 is the receptor for TNFSF8/CD30L. CD30 can interact with TRAF2 and TRAF5, and mediate the signal transduction that leads to the activation of NFkappaB. TNFRSF8 may play a role in the regulation of cellular growth and transformation of activated lymphoblasts. TNFRSF8 is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. - Proteine/Peptide
Immobilized Monoclonal Anti-Human CD30 Human Antibody, Human IgG1 at 1 µg/mL (100 µL/well) can bind FITC-Labeled Human CD30, Fc Tag (Cat. No. CD0-HF250) with a linear range of 0.08-1.3 µg/mL (QC tested).
Immobilized Human CD30 Ligand, Mouse IgG2a Fc Tag, low endotoxin (Cat. No. CDL-H525b) at 2 µg/mL (100 µL/well) can bind FITC-Labeled Human CD30, Fc Tag (Cat. No. CD0-HF250) with a linear range of 0.2-1.3 µg/mL (Routinely tested).
FITC-Labeled Human CD30, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
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