Canine CD73 / NT5E Protein, His Tag (MALS verified) (active enzyme), Unconjugated, Human

Product Overview

• Article Name: Canine CD73 / NT5E Protein, His Tag (MALS verified) (active enzyme), Unconjugated, Human
• Biozol Catalog Number: ABS-CD3-C52H5-100UG
• Supplier Catalog Number: CD3-C52H5-100ug
• Alternative Catalog Number: ABS-CD3-C52H5-100UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Canine
• Conjugation: Unconjugated

Product Description

5nucleotidase (5NT), also known as ecto5nucleotidase or CD73 (cluster of differentiation 73), is an enzyme that is encoded by the NT5E gene. CD73 commonly serves to convert AMP to adenosine. Ecto5primenucleotidase (5primeribonucleotide phosphohydrolase) catalyzes the conversion at neutral pH of purine 5prime mononucleotides to nucleosides, the preferred substrate being AMP. Other forms of 5prime nucleotidase exist in the cytoplasm and lysosomes and can be distinguished from ectoNT5 by their substrate affinities, requirement for divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate. Rare allelic variants are associated with a syndrome of adultonset calcification of joints and arteries (CALJA) affecting the iliac, femoral, and tibial arteries reducing circulation in the legs and the joints of the hands and feet causing pain. - Proteine/Peptide

Product Properties

• Molecular Weight: 59.8 kDa
• Tag: C-10*His
• NCBI: 038540011
• Buffer: 20 mM Tris, 120mM NaCl, pH7.5
• Purity: 95%
• Form: Powder
• Target: CD73

Images

Canine CD73, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.