Human CD74 / DHLAG Protein, His Tag (HPLC verified), Unconjugated

Product Overview

• Article Name: Human CD74 / DHLAG Protein, His Tag (HPLC verified), Unconjugated
• Biozol Catalog Number: ABS-CD4-H524C-1MG
• Supplier Catalog Number: CD4-H524c-1mg
• Alternative Catalog Number: ABS-CD4-H524C-1MG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Cluster of Differentiation 74 (CD74) is also known as HLA class II histocompatibility antigen gamma chain (HLADG), DHLAG, IaGAMMA, invariant chain (Abbreviated Ii). CD74 / HLADG is a polypeptide involved in the formation and transport of MHC class II protein. The cell surface form of the invariant chain is known as CD74. CD74 is upregulated in several cancers and is also expressed by nonimmune cells during inflammation. CD74 plays a critical role in MHC class II antigen processing by stabilizing peptidefree class II alpha / beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal / lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. CD74 / DHLAG also serves as cell surface receptor for the cytokine MIF. - Proteine/Peptide

Product Properties

• Molecular Weight: 19.3 kDa
• Tag: N-6*His
• NCBI: 004346
• Buffer: PBS, pH7.4
• Purity: 95%
• Form: Powder
• Target: CD74

Images

Human CD74, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

CD4-H524c-1mg