Human CD74 / DHLAG Protein, Llama IgG2b Fc Tag, low endotoxin, Unconjugated
Biozol Catalog Number:
ABS-CD4-H5258-1MG
Supplier Catalog Number:
CD4-H5258-1mg
Alternative Catalog Number:
ABS-CD4-H5258-1MG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Unconjugated
Cluster of Differentiation 74 (CD74) is also known as HLA class II histocompatibility antigen gamma chain (HLADG), DHLAG, IaGAMMA, invariant chain (Abbreviated Ii). CD74 / HLADG is a polypeptide involved in the formation and transport of MHC class II protein. The cell surface form of the invariant chain is known as CD74. CD74 is upregulated in several cancers and is also expressed by nonimmune cells during inflammation. CD74 plays a critical role in MHC class II antigen processing by stabilizing peptidefree class II alpha / beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal / lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. CD74 / DHLAG also serves as cell surface receptor for the cytokine MIF. - Proteine/Peptide
50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Purity:
95%
Form:
Powder
Target:
CD74
Human CD74 Protein, Llama IgG2b Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
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