Human CD5 Protein, His Tag, low endotoxin, Unconjugated

Product Overview

• Article Name: Human CD5 Protein, His Tag, low endotoxin, Unconjugated
• Biozol Catalog Number: ABS-CD5-H52H5-100UG
• Supplier Catalog Number: CD5-H52H5-100ug
• Alternative Catalog Number: ABS-CD5-H52H5-100UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Tcell surface glycoprotein CD5 is also known as Lymphocyte antigen T1/Leu1 and LEU1,which is phosphorylated on tyrosine residues by LYN,so CD5 can create binding sites for PTPN6/SHP1.CD5 may act as a receptor in regulating Tcell proliferation. CD5 is expressed at various developmental and activation stages on human B cells.CD5 is a well established negative regulator of TCR and BCR signalling.CD5positive cells may also prevent the emergence of autoimmunity by provision of cytokines such as IL10. Development,selection and function of different B and Tcell subsets or their preferential survival may be directly or indirectly dependent on different glycan structures associated with CD5 or CD5like molecules. - Proteine/Peptide

Product Properties

• Molecular Weight: 40.5 kDa
• Tag: C-10*His
• NCBI: 055022
• Buffer: PBS, pH7.4
• Purity: 95%
• Form: Powder
• Target: CD5

Images

Immobilized Human CD5, His Tag (Cat. No. CD5-H52H5) at 1 µg/mL (100 µL/well) can bind Monoclonal Anti-Human CD5 Antibody, Mouse IgG1 (2C8A7) with a linear range of 0.06-4 ng/mL (QC tested).

Human CD5, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.