Biotinylated Human CD5 Protein, Fc,Avitag(TM) (MALS verified)
Biozol Catalog Number:
ABS-CD5-H82F3-200UG
Supplier Catalog Number:
CD5-H82F3-200ug
Alternative Catalog Number:
ABS-CD5-H82F3-200UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Biotin
Tcell surface glycoprotein CD5 is also known as Lymphocyte antigen T1/Leu1 and LEU1,which is phosphorylated on tyrosine residues by LYN,so CD5 can create binding sites for PTPN6/SHP1.CD5 may act as a receptor in regulating Tcell proliferation. CD5 is expressed at various developmental and activation stages on human B cells.CD5 is a well established negative regulator of TCR and BCR signalling.CD5positive cells may also prevent the emergence of autoimmunity by provision of cytokines such as IL10. Development,selection and function of different B and Tcell subsets or their preferential survival may be directly or indirectly dependent on different glycan structures associated with CD5 or CD5like molecules. - Proteine/Peptide
Immobilized Biotinylated Human CD5, Fc,Avitag (Cat. No. CD5-H82F3) at 1 µg/mL (100 µL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 µg/well) plate can bind Monoclonal Anti-Human CD5 Antibody, Mouse IgG1 (2C8A7) with a linear range of 0.06-4 ng/mL (QC tested).
Biotinylated Human CD5, Fc,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
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