Biotinylated Mouse CD5 Protein, His,Avitag(TM) (MALS verified), Human

Catalog Number: ABS-CD5-M82E3-25UG
Article Name: Biotinylated Mouse CD5 Protein, His,Avitag(TM) (MALS verified), Human
Biozol Catalog Number: ABS-CD5-M82E3-25UG
Supplier Catalog Number: CD5-M82E3-25ug
Alternative Catalog Number: ABS-CD5-M82E3-25UG
Manufacturer: AcroBiosystems
Host: Human
Category: Proteine/Peptide
Species Reactivity: Mouse
Conjugation: Biotin
Tcell surface glycoprotein CD5 is also known as Lymphocyte antigen T1/Leu1 and LEU1,which is phosphorylated on tyrosine residues by LYN,so CD5 can create binding sites for PTPN6/SHP1.CD5 may act as a receptor in regulating Tcell proliferation. CD5 is expressed at various developmental and activation stages on human B cells.CD5 is a well established negative regulator of TCR and BCR signalling.CD5positive cells may also prevent the emergence of autoimmunity by provision of cytokines such as IL10. Development,selection and function of different B and Tcell subsets or their preferential survival may be directly or indirectly dependent on different glycan structures associated with CD5 or CD5like molecules. - Proteine/Peptide
Molecular Weight: 41.4 kDa
Tag: C-10*His & C-Avi
NCBI: 13379
Buffer: PBS, pH7.4
Purity: 90%
Form: Powder
Target: CD5
Biotinylated Mouse CD5 Protein, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.