Biotinylated Mouse CD155 / PVR Protein, His,Avitag(TM), Human
Biozol Catalog Number:
ABS-CD5-M82E4-200UG
Supplier Catalog Number:
CD5-M82E4-200ug
Alternative Catalog Number:
ABS-CD5-M82E4-200UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Mouse
Conjugation:
Biotin
CD155 is a Type I transmembrane glycoprotein in the immunoglobulin superfamily. Commonly known as Poliovirus Receptor (PVR) due to its involvement in the cellular poliovirus infection in primates, CD155s normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. CD155/PVR was originally isolated based on its ability to mediate polio virus attachment to host cells. The fulllength (or CD155 alpha isoform) is synthesized as a 417 amino acid (aa) precursor that contains a 20 aa signal sequence, a 323 aa extracellular region, a 24 aa TM segment and a 50 aa cytoplasmic tail. The extracellular region contains one N terminal V type and two C2 type Ig like domains. CD155 is a transmembrane protein with 3 extracellular immunoglobulinlike domains, D1D3, where D1 is recognized by the virus. Low resolution structures of CD155 complexed with poliovirus have been obtained using electron microscopy while a high resolution structures of theectodomain D1 and D2 of CD155 were solved by xray crystallography. - Proteine/Peptide
Immobilized Mouse TIGIT, Fc Tag (Cat. No. TIT-M5257) at 5 µg/mL (100 µL/well) can bind Biotinylated Mouse CD155 Protein, His,Avitag (Cat. No. CD5-M82E4) with a linear range of 0.3-20 ng/mL (QC tested).
Biotinylated Mouse CD155 Protein, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
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