Rhesus macaque CD155 / PVR Protein, His Tag (MALS verified), Unconjugated, Human

Catalog Number: ABS-CD5-R52H5-100UG
Article Name: Rhesus macaque CD155 / PVR Protein, His Tag (MALS verified), Unconjugated, Human
Biozol Catalog Number: ABS-CD5-R52H5-100UG
Supplier Catalog Number: CD5-R52H5-100ug
Alternative Catalog Number: ABS-CD5-R52H5-100UG
Manufacturer: AcroBiosystems
Host: Human
Category: Proteine/Peptide
Species Reactivity: Monkey
Conjugation: Unconjugated
CD155 is a Type I transmembrane glycoprotein in the immunoglobulin superfamily. Commonly known as Poliovirus Receptor (PVR) due to its involvement in the cellular poliovirus infection in primates, CD155s normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. CD155/PVR was originally isolated based on its ability to mediate polio virus attachment to host cells. The fulllength (or CD155 alpha isoform) is synthesized as a 417 amino acid (aa) precursor that contains a 20 aa signal sequence, a 323 aa extracellular region, a 24 aa TM segment and a 50 aa cytoplasmic tail. The extracellular region contains one N terminal V type and two C2 type Ig like domains. CD155 is a transmembrane protein with 3 extracellular immunoglobulinlike domains, D1D3, where D1 is recognized by the virus. Low resolution structures of CD155 complexed with poliovirus have been obtained using electron microscopy while a high resolution structures of theectodomain D1 and D2 of CD155 were solved by xray crystallography. - Proteine/Peptide
Molecular Weight: 36.3 kDa
Tag: C-10*His
NCBI: 0
Buffer: PBS, pH7.4
Purity: 90%
Form: Powder
Target: CD155
CD5-R52H5-100ug
Immobilized Rhesus macaque CD155, His Tag (Cat. No. CD5-R52H5) at 5 µg/mL (100 µL/well) can bind Cynomolgus / Rhesus macaque TIGIT, Fc Tag (Cat. No. TIT-C5254) with a linear range of 0.02-0.313 µg/mL (QC tested).
Immobilized Rhesus macaque CD155, His Tag (Cat. No. CD5-R52H5) at 5 µg/mL (100 µL/well) can bind Biotinylated Human DNAM-1, Fc,Avitag (Cat. No. DN1-H82F9) with a linear range of 10-156 ng/mL (Routinely tested).
Rhesus macaque CD155, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.