Mouse CD206 / MMR Protein, His Tag (HPLC verified), Unconjugated, Human

Product Overview

• Article Name: Mouse CD206 / MMR Protein, His Tag (HPLC verified), Unconjugated, Human
• Biozol Catalog Number: ABS-CD6-M52H7-1MG
• Supplier Catalog Number: CD6-M52H7-1mg
• Alternative Catalog Number: ABS-CD6-M52H7-1MG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Mouse
• Conjugation: Unconjugated

Product Description

Mrc1 is a conserved checkpoint mediator protein that transduces the replication stress signal to the downstream effector kinase. Mrc1 and its vertebrate homologue Claspin serve as a mediator for replication stress checkpoint signaling, receiving the signal from Mec1/Rad3/ATR sensor kinase and transmitting it to the effector Rad53/Cds1/Chk1 kinase. The loss of mrc1 checkpoint activity results in the aberrant activation of late/dormant origins in the presence of hydroxyurea. Tumorassociated macrophages (TAMs) expressing the multiligand endocytic receptor mannose receptor (CD206/MRC1) contribute to tumor immunosuppression, angiogenesis, metastasis, and relapse. - Proteine/Peptide

Product Properties

• Molecular Weight: 157.3 kDa
• Tag: C-10*His
• NCBI: 61830
• Buffer: PBS, pH7.4
• Purity: 90%
• Form: Powder
• Target: CD206

Images

Immobilized Mannan from Saccharomyces cerevisiae at 20 µg/mL (100 µL/well) can bind Mouse CD206 Protein, His Tag (Cat. No. CD6-M52H7) with a linear range of 0.078-1.25 µg/mL (QC tested).

Mouse CD206 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.